April 25, 2025
2 min learn
Key takeaways:
- Refractive surgical procedure planning wants a paradigm shift to a extra potential method.
- Simulation software program designed to construct a digital eye might assist individualize remedy.
LOS ANGELES — Simulation software program designed to construct a digital eye might assist predict the outcomes of laser imaginative and prescient correction earlier than surgical procedure, leading to a extra individualized remedy method, in accordance with a speaker right here.
At Refractive Day on the American Society of Cataract and Refractive Surgical procedure assembly, William J. Dupps Jr., MS, PhD, MD, FARVO, stated that the present refractive surgical procedure paradigm is retrospective, probabilistic, minimally customized and inhabitants primarily based. A shift within the method to surgical planning could also be wanted.
“The brand new method, hopefully, could be extra potential, extra deterministic and extra individualized for the attention in entrance of us,” he stated.
A promising instrument to yield this paradigm shift, Dupps stated, is computational modeling, particularly the finite factor methodology. This includes making a “digital twin” of a watch by means of structural engineering.
Utilizing tomography, the 3D geometry of a cornea is obtained and imported into software program that builds a complete eye mannequin utilizing the affected person’s demographic info together with axial eye size and different variables.
“At that time, the person can choose a surgical procedure or process they want to simulate,” Dupps stated.
Dupps and colleagues have constructed modules that simulate procedures together with LASIK, PRK, lenticule extraction, cross-linking and astigmatic keratotomy.
“The laser imaginative and prescient correction method is one thing we now have been very targeted on lately,” he stated. “We’re as actually as attainable simulating the fact of the process we’re fascinated with.”
To validate the software program’s efficacy, Dupps and colleagues collected information from 19 LASIK circumstances and in contrast the simulated predicted outcomes with the precise outcomes from 3 months postoperatively, exhibiting a “very tight correlation.” Nevertheless, there are limitations that have to be addressed to enhance the simulation’s accuracy.
“We’re assuming that everyone has the identical biomechanical properties of the cornea,” Dupps stated. “Even with that assumption, we are able to get fairly shut. However we have to do higher.”
To enhance simulation accuracy, Dupps really useful measuring corneal hysteresis earlier than surgical procedure.
“We don’t have the reply previous to modeling this, however we are able to get nearer to the fitting final result if we consider that straightforward marker,” he stated. “That provides me nice hope that, once we incorporate extra spatially delicate approaches like Brillouin microscopy and others, we are able to even additional refine these outcomes.”
Sources/Disclosures
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Dupps WJ. Simulation software program to foretell postoperative form and biomechanical outcomes earlier than laser imaginative and prescient correction. Introduced at: American Society of Cataract and Refractive Surgical procedure assembly; April 25-28, 2025; Los Angeles.
Disclosures:
Dupps reviews having mental property in biomechanical measurement and modeling (Cleveland Clinic), consulting for Alcon and receiving grant funding from NIH/NEI.
