April 26, 2025
2 min watch
NATIONAL HARBOR, Md. — GLP-1 receptor agonists are efficient weight-loss medicines, however they might additionally lower muscle mass, elevating issues concerning the long-term results of those medicine, based on Christos S. Katsanos, PhD.
“We don’t know precisely what the causes are and the extent of that muscle loss, however it’s a massive concern amongst clinicians treating sufferers with weight problems,” he instructed Healio.
On this video, Katsanos, an affiliate professor within the College of Life Sciences at Arizona State College and adjunct college member at Mayo Clinic Arizona, opinions two methods that will assist protect muscle mass in sufferers receiving GLP-1 receptor agonists: vitamin and train.
“Protein is a crucial element to reinforce skeletal muscle,” Katsanos mentioned. “Protein decreases throughout pathophysiological circumstances related to the lack of skeletal muscle. By manipulating protein synthesis, we will regulate and probably stop lack of skeletal muscle. The best way we will do that’s by means of dietary interventions.”
Along with dietary protein, train — particularly, cardio train — can additional “stimulate protein synthesis of the skeletal muscle of those sufferers on GLP-1 medicines,” he mentioned.
Reference:
- Katsanos CS. Muscle security: Addressing GLP-1 agonist issues with train & vitamin. Offered at: Weight problems Medication 2025. April 23-27, 2025; Nationwide Harber, Md.
For extra info:
Christos S. Katsanos, PhD, may be reached at primarycare@healio.com.
